Confidence level
Moderate evidence
257 studies
GABA (Gamma-Aminobutyric Acid)
Last reviewed: 4/3/2026
Absorption
✦Take on an empty stomach 30-60 minutes before bedtime for sleep support. Peak blood levels occur approximately 30 minutes after oral administration. Avoid combining with sedative medications or alcohol.
Daily Dose
⚖
Common dose: 100-200 mg/day
RDA: No established RDA
Upper limit: No established upper limit; up to 300 mg/day used in studies
Best form: Biosynthetic GABA (PharmaGABA) or fermented GABA
Timing: 30-60 minutes before bedtime
A 2020 systematic review concluded evidence for stress benefits is limited and for sleep is very limited.
Effects
Food Sources
- Fermented foods (kimchi, tempeh)Varies widely
- Tomatoes~62 mg per 100g
- Green tea~0.2-0.5 mg per cup