What is Phosphatidylserine?

Phosphatidylserine is a phospholipid, a type of fat molecule that is a key component of cell membranes, particularly in the brain. Naturally found in foods such as soybeans, white beans, and organ meats, it plays a crucial role in maintaining cellular structure and function. Research on phosphatidylserine has predominantly focused on its potential benefits for cognitive health. Studies suggest that it may help support memory function, improve attention, and possibly reduce cognitive decline with

How many studies on Phosphatidylserine are available?

NutriVouch references 320 human studies on Phosphatidylserine, all peer-reviewed and indexed on PubMed.

Is Phosphatidylserine effective for Cognitive Function?

For Cognitive Function, Phosphatidylserine has an effectiveness score of 5/10 — moderate evidence — works in some populations. Based on 16 relevant studies.

Is Phosphatidylserine effective for Memory Improvement?

For Memory Improvement, Phosphatidylserine has an effectiveness score of 5/10 — moderate evidence — works in some populations. Based on 12 relevant studies.

Is Phosphatidylserine effective for Stress Relief?

For Stress Relief, Phosphatidylserine has an effectiveness score of 4/10 — weak or limited clinical evidence. Based on 20 relevant studies.

Is Phosphatidylserine effective for Focus & Concentration?

For Focus & Concentration, Phosphatidylserine has an effectiveness score of 4/10 — weak or limited clinical evidence. Based on 20 relevant studies.

Is Phosphatidylserine effective for Mood Support?

For Mood Support, Phosphatidylserine has an effectiveness score of 3/10 — weak or limited clinical evidence. Based on 6 relevant studies.

Confidence level

Moderate evidence

320 studies

Phosphatidylserine

Absorption

✦Take with food to improve absorption, particularly if the meal contains fat. No significant absorption interactions known.

Daily Dose

⚖

Common dose: 100–300 mg daily

RDA: No official RDA established

Upper limit: Not established

Best form: Phosphatidylserine derived from soy lecithin

Timing: With meals to enhance absorption

Higher doses up to 600 mg have been used in studies for cognitive decline. Long-term safety of high doses is not well established; consult a healthcare provider if considering high doses.

Effects

🎯 Focus & Concentration

4.020 studies›

🌤 Mood Support

3.06 studies›

Food Sources

Soy lecithin565mg per 100g
Atlantic mackerel480mg per 100g
Chicken heart414mg per 100g
Atlantic herring360mg per 100g
Beef liver290mg per 100g