What is Alpha-Lipoic Acid?

Alpha-lipoic acid (ALA) is a naturally occurring compound that belongs to the class of organosulfur compounds. It is found in small amounts in foods such as spinach, broccoli, and potatoes, and it can also be synthesized by the human body. ALA is best known for its antioxidant properties, as it plays a crucial role in combating oxidative stress, which is linked to aging and various chronic diseases. Research indicates that alpha-lipoic acid may support general health by influencing glucose metab

How many studies on Alpha-Lipoic Acid are available?

NutriVouch references 299 human studies on Alpha-Lipoic Acid, all peer-reviewed and indexed on PubMed.

Is Alpha-Lipoic Acid effective for Blood Sugar Balance?

For Blood Sugar Balance, Alpha-Lipoic Acid has an effectiveness score of 6/10 — moderate evidence — works in some populations. Based on 19 relevant studies.

Is Alpha-Lipoic Acid effective for Weight Management?

For Weight Management, Alpha-Lipoic Acid has an effectiveness score of 4/10 — weak or limited clinical evidence. Based on 15 relevant studies.

Is Alpha-Lipoic Acid effective for Anti-Inflammation?

For Anti-Inflammation, Alpha-Lipoic Acid has an effectiveness score of 4/10 — weak or limited clinical evidence. Based on 18 relevant studies.

Is Alpha-Lipoic Acid effective for Cognitive Function?

For Cognitive Function, Alpha-Lipoic Acid has an effectiveness score of 3/10 — weak or limited clinical evidence. Based on 12 relevant studies.

Is Alpha-Lipoic Acid effective for Fat Metabolism?

For Fat Metabolism, Alpha-Lipoic Acid has an effectiveness score of 3/10 — weak or limited clinical evidence. Based on 7 relevant studies.

Confidence level

Strong evidence

299 studies

Alpha-Lipoic Acid

Absorption

✦Best absorbed on an empty stomach, ideally 30 minutes before meals. Avoid taking with calcium or magnesium supplements as they may interfere with absorption.

Daily Dose

⚖

Common dose: 300–600 mg daily

RDA: No official RDA established

Upper limit: Not established

Best form: R-Alpha-Lipoic Acid

Timing: Take on an empty stomach for better absorption.

Alpha-Lipoic Acid is both water- and fat-soluble, which may enhance its absorption. Consult a healthcare provider before use, especially if you have a medical condition or are taking other medications.

Effects

📊 Blood Sugar Balance

Food Sources

Spinach3.2mg per 100g
Broccoli0.9mg per 100g
Tomatoes0.6mg per 100g
Brussels sprouts0.5mg per 100g
Peas0.3mg per 100g