Dehydroepiandrosterone (DHEA) is a hormone that falls into the category of steroid hormones and is naturally produced by the adrenal glands, gonads, and brain. In the body, DHEA serves as a precursor to male and female sex hormones, including testosterone and estrogen. Research has explored its potential effects on general health, particularly in areas such as aging, bone density, and mood. Some studies suggest that DHEA supplementation might support bone health and improve symptoms of depressio

How many studies on DHEA are available?

NutriVouch references 352 human studies on DHEA, all peer-reviewed and indexed on PubMed.

Is DHEA effective for Fertility Support?

For Fertility Support, DHEA has an effectiveness score of 5/10 — moderate evidence — works in some populations. Based on 15 relevant studies.

Is DHEA effective for Menopause Support?

For Menopause Support, DHEA has an effectiveness score of 5/10 — moderate evidence — works in some populations. Based on 16 relevant studies.

Is DHEA effective for Depression Support?

For Depression Support, DHEA has an effectiveness score of 4/10 — weak or limited clinical evidence. Based on 19 relevant studies.

Is DHEA effective for Bone Health?

For Bone Health, DHEA has an effectiveness score of 4/10 — weak or limited clinical evidence. Based on 17 relevant studies.

Is DHEA effective for Skin Health?

For Skin Health, DHEA has an effectiveness score of 4/10 — weak or limited clinical evidence. Based on 28 relevant studies.

Confidence level

Strong evidence

352 studies

DHEA

Absorption

✦Can be taken with or without food. No significant absorption interactions known.

Daily Dose

⚖

Common dose: 25–50 mg daily.

RDA: No official RDA established.

Upper limit: Not established.

Best form: Micronized DHEA for improved absorption.

Timing: With food to enhance absorption.

DHEA levels decline with age; supplementation may be considered for age-related decline. Consult a healthcare provider before use, especially for individuals with hormone-sensitive conditions.

Effects