Depression Support

Supplements studied for their role in managing depressive symptoms.

57 supplements have studies linked to this goal. St. John's Wort scores highest (8/10), followed by Saffron Extract (7/10) and EPA (Eicosapentaenoic Acid) (6/10). 12 of them reach moderate or strong support — the rest are thinly studied or showed little effect.

Supplements rated for Depression Support

How to read these scores

The 0–10 score reflects how well the evidence supports a supplement for this specific goal, independent of how much it has been studied overall. It is an editorial rating checked against meta-analyses — how we set it.