Sulforaphane is safe in unlimited amounts
9.0Strong
evidence
evidence
The Claim
Some consumers believe that because sulforaphane is derived from vegetables, it is entirely safe to consume in large quantities without any risk of side effects.
Origin
This misconception likely arises from the general perception that natural substances are always safe, coupled with a lack of regulation in the supplement market.
What Science Says
While sulforaphane is generally considered safe when consumed in amounts typically found in food, high doses of supplements can lead to gastrointestinal discomfort and other side effects. Research, including randomized controlled trials, shows that the safety profile is dose-dependent, and excessive intake could pose risks.
Verdict
False
Sources
- PMID:29288567 Isothiocyanates and Xenobiotic Detoxification.
- PMID:36771448 Sulforaphane Ameliorates Nonalcoholic Fatty Liver Disease Induced by High-Fat and High-Fructose Diet via LPS/TLR4 in the Gut-Liver Axis.
- PMID:28412310 Increased seizure susceptibility and other toxicity symptoms following acute sulforaphane treatment in mice.