St. John's Wort cures all forms of depression
evidence
The Claim
Many people believe that St. John's Wort is a universal remedy for depression, effective for all types and severities of the condition. This belief is often tied to its natural origins, leading individuals to assume it's a safe alternative to prescription medications.
Origin
This myth likely originates from media reports and anecdotal evidence, as well as marketing by supplement companies emphasizing its use for mood enhancement.
What Science Says
Research suggests that St. John's Wort can be effective for mild to moderate depression. A meta-analysis of randomized controlled trials (RCTs) highlights its efficacy in these cases, showing similar effects to standard antidepressants with fewer side effects. However, for severe depression, evidence is lacking and suggests it may not be as effective compared to prescribed medications.
Verdict
Partially True
Sources
- PMID:28064110 Clinical use of Hypericum perforatum (St John's wort) in depression: A meta-analysis.
- PMID:36226689 The efficacy and safety of St. John's wort extract in depression therapy compared to SSRIs in adults: A meta-analysis of randomized clinical trials.
- PMID:35311615 Clinician guidelines for the treatment of psychiatric disorders with nutraceuticals and phytoceuticals: The World Federation of Societies of Biological Psychiatry (WFSBP) and Canadian Network for Mood and Anxiety Treatments (CANMAT) Taskforce.