Phosphatidylserine is a natural stress reliever
6.0Moderate
evidence
evidence
The Claim
It is often claimed that phosphatidylserine can significantly reduce stress levels, providing a calming effect similar to that of anti-anxiety medications.
Origin
The origin of this myth can be traced back to early studies and supplement marketing emphasizing stress reduction benefits without clear evidence.
What Science Says
Research, including a few small-scale RCTs, shows that phosphatidylserine may help modulate cortisol levels in response to stress, but the effects are modest. A meta-analysis found that while there is some cortisol modulation, it does not translate into significant reductions in perceived stress or anxiety levels. Further large-scale studies are needed to confirm these findings.
Verdict
Partially True