DIM is safe for everyone to use without side effects
6.0Moderate
evidence
evidence
The Claim
There is a misconception that DIM, being a compound derived from vegetables, is completely safe for everyone to use without any risk of side effects.
Origin
This belief is rooted in the natural origin of DIM, as it is derived from cruciferous vegetables, leading people to assume it carries no risk.
What Science Says
While DIM is generally considered safe at recommended doses, some studies and case reports have documented side effects such as gastrointestinal distress and headaches. Additionally, high doses or long-term use can lead to more serious adverse effects, and it may interact with certain medications. Safety profiles from clinical trials suggest that while DIM is safe for most, it is not universally free of side effects.
Verdict
Mostly False
Sources
- PMID:33870175 Efficacy and safety of supplemental melatonin for delayed sleep-wake phase disorder in children: an overview.
- PMID:26918831 Anti-cancer drug 3,3'-diindolylmethane activates Wnt4 signaling to enhance gastric cancer cell stemness and tumorigenesis.
- PMID:38495547 Evaluating Common Ingredients Contained in Dietary Acne Supplements: An Evidence-Based Review.