5-HTP improves sleep quality
Partially trueThe Claim
It is commonly believed that 5-HTP can enhance sleep quality by increasing serotonin, which is a precursor to melatonin, the sleep hormone.
Origin
The myth likely arises from the known biological pathway where serotonin is converted into melatonin, suggesting a plausible mechanism for improving sleep.
What Science Says
Studies on 5-HTP and sleep have shown mixed results. Some preliminary research, including small RCTs, suggests improvements in sleep latency and duration, but these studies are limited by size and quality. A comprehensive review points out that while 5-HTP may have some positive effects on sleep, more robust evidence is necessary to confirm these benefits.
Verdict
Partially True
Sources
- PMID:38309227 The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial.
- PMID:34403081 Preliminary finding of a randomized, double-blind, placebo-controlled, crossover study to evaluate the safety and efficacy of 5-hydroxytryptophan on REM sleep behavior disorder in Parkinson's disease.